HLA Mismatching Favoring Host-Versus-Graft NK Cell Activity Via KIR3DL1 Is Associated With Improved Outcomes Following Lung Transplantation
نویسندگان
چکیده
منابع مشابه
the impact of hla-e polymorphisms in graft-versus-host disease following hla-e matched allogeneic hematopoietic stem cell transplantation
the non-classical mhc class-i mainly involves in the regulation of innate immune responses where hla-e plays a significant role in the cell identification by natural killer cells. hla-e is a main regulatory ligand for natural killer cells and given the importance of these effector cells in hematopoietic stem cell transplantation, we investigated the effect of hla-e polymorphisms on post-h...
متن کاملRelationship between Molecular Chimerism and Graft Versus Host Disease after Allogenic Hematopoietic Stem Cell Transplantation
Background: Bone marrow transplantation (BMT) is considered as a curative therapy for a broad range of diseases. However, complications such as relapse and graft versus host disease (GVHD) may be observed following BMT. Chimerism analysis serves as a reliable indicator of transplant outcome. Complete chimerism refers to the complete replacement of hematopoietic system by donor cells, while mixe...
متن کاملGraft-versus-host disease following autologous transplantation.
269 K .T., a 76-year-old woman, was diagnosed with stage IIA multiple myeloma in 2007 when she presented with severe back pain. K.T. underwent kyphoplasty, a minimally invasive surgery to relieve compression fractures, followed by eight cycles of lenalidomide with a good response. Peripheral blood stem cells were collected after mobilization with filgrastim and plerixafor. She was admitted to t...
متن کاملThe impact of HLA-E polymorphisms in graft-versus-host disease following HLA-E matched allogeneic hematopoietic stem cell transplantation.
The non-classical MHC class-I mainly involves in the regulation of innate immune responses where HLA-E plays a significant role in the cell identification by natural killer cells. HLA-E is a main regulatory ligand for natural killer cells and given the importance of these effector cells in hematopoietic stem cell transplantation, we investigated the effect of HLA-E polymorphisms on post-hematop...
متن کاملPediatric lung transplantation for graft-versus-host disease following bone marrow transplantation.
Nine years after receiving a bone marrow transplant for aplastic anemia, a 14-year-old girl with severe pulmonary disease associated with graft-versus-host disease received a double lung transplant. Subsequent to lung transplant, her lung function improved dramatically (FEV1 increasing from 20 to 73 percent predicted normal, residual volume decreasing from 316 to 130 percent predicted normal va...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: American Journal of Transplantation
سال: 2017
ISSN: 1600-6135
DOI: 10.1111/ajt.14295